1-Cbz-3-Methylpiperidine-3-carboxylic Acid - Names and Identifiers
Name | 1-N-Cbz-3-Methylpiperidine-3-carboxylic acid
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Synonyms | 1-Cbz-3-Methylpiperidine-3-carboxylic Acid 1-Cbz-3-methyl-3-piperidinecarboxylic acid N-Cbz-3-Methylpiperidine-3-carboxylic acid 1-N-Cbz-3-Methylpiperidine-3-carboxylic acid 1-N-Cbz-3-Methyl-Piperidine-3-Carboxylic Acid 1-[(benzyloxy)carbonyl]-3-methylpiperidine-3-carboxylic acid 3-Methyl-1,3-piperidinedicarboxylic acid 1-(phenylmethyl) ester 1,3-Piperidinedicarboxylic acid, 3-methyl-, 1-(phenylmethyl) ester
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CAS | 174543-78-3
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InChI | InChI=1/C15H19NO4/c1-15(13(17)18)8-5-9-16(11-15)14(19)20-10-12-6-3-2-4-7-12/h2-4,6-7H,5,8-11H2,1H3,(H,17,18) |
1-Cbz-3-Methylpiperidine-3-carboxylic Acid - Physico-chemical Properties
Molecular Formula | C15H19NO4
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Molar Mass | 277.32 |
Density | 1.224 |
Boling Point | 440.3±45.0 °C(Predicted) |
pKa | 4.52±0.20(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.555 |
1-Cbz-3-Methylpiperidine-3-carboxylic Acid - Introduction
acid is an organic compound with the chemical formula C23H23NO3. It is a white solid, soluble in organic solvents such as methylene chloride and ethanol.
The acid is often used as a protecting group in organic synthesis. It is obtained by reacting a carboxyl group with an amino group and removing the protecting group under specific conditions to obtain the desired product. In addition, it can also be used in the preparation of pharmaceuticals, pesticides and other organic compounds.
The method for preparing aryl acid is generally to react 3-piperidinecarboxylic acid with 3-chloro-3-methyl-3-piperidinyl copper chloride (Cbz-Cl) under alkaline conditions. The reaction is usually carried out at room temperature, and the pure product is obtained by crystallization, washing and drying.
Regarding safety information, acid should be considered a hazardous chemical. During handling and handling, wear appropriate personal protective equipment (such as gloves, glasses and protective clothing) to avoid contact with skin and eyes. During use, ensure adequate ventilation and keep away from open flames and heat sources. If the compound is accidentally ingested or inhaled, seek medical attention immediately.
Last Update:2024-04-09 20:02:46